55 Terms Defined
Longevity & Biohacking Glossary
Reviewed by Evolve Longevity Medical Team · Last updated April 2026
A comprehensive reference of key terms in longevity medicine, regenerative science, biohacking, and anti-aging research. Each definition is written for clarity, accuracy, and clinical relevance.
Published by Evolve Longevity — Miami Beach's premier longevity and biohacking clinic.
A
- ATP (Adenosine Triphosphate)#
- Adenosine triphosphate is the primary energy currency of every cell in the human body, produced mainly within the mitochondria through oxidative phosphorylation. ATP fuels critical biological processes including muscle contraction, nerve impulse transmission, and cellular repair. Declining ATP production is a hallmark of aging and is closely linked to reduced physical performance and slower recovery.
- Autophagy#
- Autophagy is the body's innate cellular recycling process in which damaged or dysfunctional organelles and proteins are broken down and repurposed for new cellular construction. This self-cleaning mechanism is essential for maintaining cellular health and preventing the accumulation of toxic debris that contributes to aging and chronic disease. Autophagy can be stimulated through fasting, exercise, and certain pharmacological agents such as rapamycin.
- Anti-Aging Medicine#
- Anti-aging medicine is a clinical specialty focused on the early detection, prevention, and reversal of age-related decline using evidence-based interventions. It encompasses hormone optimization, regenerative therapies, nutritional biochemistry, and advanced diagnostics to extend both lifespan and healthspan. Unlike conventional medicine that treats disease after onset, anti-aging medicine proactively targets the root mechanisms of biological aging.Explore our anti-aging treatments
B
- Bioavailability#
- Bioavailability refers to the proportion of a nutrient, supplement, or drug that enters systemic circulation and is available for biological activity after administration. Oral supplements typically have lower bioavailability due to digestive breakdown and first-pass hepatic metabolism, while intravenous delivery achieves near-100% bioavailability. This distinction is why IV therapy is preferred for delivering high-dose vitamins, minerals, and therapeutic compounds.Learn about IV therapy for maximum bioavailability
- Biohacking#
- Biohacking is the practice of using science, technology, and self-experimentation to optimize biological function and enhance human performance beyond baseline levels. It encompasses a wide spectrum of interventions ranging from nutrition and sleep optimization to advanced technologies like photobiomodulation, PEMF therapy, and peptide protocols. The biohacking philosophy treats the human body as a system that can be measured, monitored, and systematically improved.
- Biological Age#
- Biological age is a measurement of how old your body appears functionally at the cellular and molecular level, which may differ significantly from chronological age. It is assessed through biomarkers such as DNA methylation patterns, telomere length, inflammatory markers, and metabolic function. Two people of the same chronological age can have biological ages that differ by decades depending on genetics, lifestyle, and environmental exposures.Take our biological age quiz
- BPC-157#
- BPC-157 (Body Protection Compound-157) is a synthetic peptide derived from a naturally occurring protein found in human gastric juice. It has demonstrated powerful tissue-healing properties in preclinical studies, accelerating the repair of muscles, tendons, ligaments, and the gastrointestinal lining. BPC-157 works in part by promoting angiogenesis (new blood vessel formation) and modulating growth factor expression at injury sites.Learn about our BPC-157 peptide therapy
C
- Cellular Senescence#
- Cellular senescence is a state in which cells permanently stop dividing but resist apoptosis (programmed cell death), instead remaining metabolically active and secreting inflammatory molecules known as the senescence-associated secretory phenotype (SASP). The accumulation of senescent cells is a primary driver of chronic inflammation, tissue dysfunction, and age-related disease. Clearing these so-called zombie cells through senolytic therapies is a leading strategy in longevity medicine.
- Chronological Age#
- Chronological age is simply the number of years a person has been alive since birth, measured by the calendar. Unlike biological age, chronological age does not reflect the functional state of cells, tissues, or organ systems. Longevity medicine focuses on widening the gap between chronological age and biological age, aiming to keep biological age significantly younger than the calendar would suggest.
- Collagen#
- Collagen is the most abundant structural protein in the human body, forming the primary scaffold of skin, bones, cartilage, tendons, and connective tissue. Natural collagen production declines by approximately 1% per year after age 25, leading to wrinkles, joint stiffness, and reduced structural integrity. Regenerative therapies including peptides like GHK-Cu and exosome treatments can stimulate new collagen synthesis to counteract this decline.Explore collagen-boosting peptide therapy
- Cytokines#
- Cytokines are small signaling proteins released by cells of the immune system that regulate inflammation, immune responses, and cell-to-cell communication throughout the body. They can be broadly classified as pro-inflammatory (such as IL-6 and TNF-alpha) or anti-inflammatory (such as IL-10). Chronic elevation of pro-inflammatory cytokines, sometimes called a cytokine storm, is a hallmark of aging and is implicated in conditions ranging from autoimmune disease to neurodegeneration.
D
- DEXA Scan#
- DEXA (Dual-Energy X-ray Absorptiometry) is a medical imaging technology that provides precise measurements of bone mineral density, lean muscle mass, and body fat distribution, including visceral adipose tissue. It is considered the gold standard for body composition analysis, offering far greater accuracy than BMI or bioelectrical impedance scales. Regular DEXA scans allow clinicians and patients to track changes in muscle, fat, and bone health over time with clinical precision.Book a DEXA scan at Evolve Longevity
- Detoxification#
- Detoxification is the physiological process by which the body neutralizes and eliminates harmful substances including environmental toxins, heavy metals, metabolic waste products, and xenobiotics. The liver, kidneys, lymphatic system, and skin are the primary organs of detoxification. Clinical detoxification protocols use targeted binders, supportive nutrients like glutathione, and drainage support to enhance the body's natural eliminatory pathways.View our clinical detox protocols
E
- EBOO (Extracorporeal Blood Oxygenation and Ozonation)#
- EBOO is an advanced blood purification therapy in which a patient's blood is drawn, passed through a specialized filtration and ozonation system, and returned to the body in a continuous loop. This process enhances oxygen delivery to tissues, modulates the immune system, reduces pathogen load, and supports detoxification. EBOO is considered one of the most powerful ozone-based therapies available and is used for chronic infections, autoimmune conditions, and overall vitality optimization.Learn about EBOO therapy at Evolve Longevity
- Epigenetics#
- Epigenetics is the study of heritable changes in gene expression that occur without alterations to the underlying DNA sequence, primarily through mechanisms such as DNA methylation, histone modification, and non-coding RNA regulation. Environmental factors including diet, stress, toxin exposure, and exercise directly influence epigenetic markers, meaning lifestyle choices can literally turn genes on or off. Epigenetic clocks based on DNA methylation patterns are now the most accurate biomarkers for measuring biological age.
- Epithalon#
- Epithalon (also spelled Epitalon) is a synthetic tetrapeptide based on the naturally occurring epithalamin produced by the pineal gland. It is the only known substance demonstrated in research to activate telomerase, the enzyme responsible for lengthening telomeres at the ends of chromosomes. By supporting telomere maintenance, Epithalon is studied for its potential to slow cellular aging, improve sleep quality through melatonin regulation, and enhance immune function.Learn about Epithalon peptide therapy
- Exosomes#
- Exosomes are nanoscale extracellular vesicles (30-150 nanometers) secreted by cells that carry proteins, lipids, mRNA, and microRNA to facilitate intercellular communication. In regenerative medicine, exosomes derived from mesenchymal stem cells are used therapeutically to promote tissue repair, reduce inflammation, and reprogram damaged cells without the regulatory and immunological challenges associated with live cell transplantation. They represent a cell-free approach to harnessing the regenerative signaling power of stem cells.Explore exosome therapy at Evolve Longevity
F
- Free Radicals#
- Free radicals are highly reactive, unstable molecules with unpaired electrons that damage cellular structures including DNA, proteins, and lipid membranes through a process called oxidation. They are generated as natural byproducts of mitochondrial energy production but are also produced in excess by environmental stressors such as UV radiation, pollution, and poor diet. The cumulative oxidative damage caused by free radicals is a central mechanism in the free radical theory of aging.
- Functional Medicine#
- Functional medicine is a patient-centered clinical approach that identifies and addresses the root causes of disease rather than merely managing symptoms. It uses advanced diagnostic testing, including comprehensive blood panels, genetic analysis, and microbiome assessment, to create individualized treatment protocols. Functional medicine practitioners view the body as an interconnected system and consider factors such as gut health, hormonal balance, toxin burden, and nutrient status when designing interventions.Explore our functional medicine approach
G
- GHK-Cu (Copper Peptide)#
- GHK-Cu is a naturally occurring tripeptide bound to a copper ion that is found in human plasma, saliva, and urine, with circulating levels that decline significantly with age. It is a potent stimulator of collagen synthesis, wound healing, and skin remodeling, and has demonstrated anti-inflammatory and antioxidant properties in research. GHK-Cu is used in longevity medicine both topically for skin rejuvenation and systemically for tissue repair and anti-aging gene expression modulation.Learn about GHK-Cu peptide therapy
- Glutathione#
- Glutathione is a tripeptide (glutamate, cysteine, glycine) produced in every cell of the body that serves as the master antioxidant and primary detoxification agent. It neutralizes free radicals, regenerates other antioxidants like vitamins C and E, and is essential for phase II liver detoxification of heavy metals and environmental toxins. Glutathione levels naturally decline with age, and IV or push delivery is preferred over oral supplementation due to poor gastrointestinal absorption.Learn about our glutathione IV push
- Growth Hormone (GH / HGH)#
- Growth hormone is a peptide hormone secreted by the anterior pituitary gland that plays a critical role in cell regeneration, body composition, metabolism, and tissue repair throughout life. GH production peaks during adolescence and declines steadily thereafter, contributing to age-related loss of muscle mass, increased body fat, thinning skin, and reduced recovery capacity. Longevity clinics use growth hormone-releasing peptides such as CJC-1295, Ipamorelin, and Sermorelin to naturally stimulate endogenous GH production rather than administering exogenous hormone directly.Explore growth hormone peptides
H
- HBOT (Hyperbaric Oxygen Therapy)#
- Hyperbaric oxygen therapy involves breathing 100% pure oxygen inside a pressurized chamber at pressures greater than normal atmospheric levels, typically 1.5 to 3.0 atmospheres absolute (ATA). This dramatically increases dissolved oxygen in the blood plasma, enabling oxygen to reach tissues with compromised circulation and stimulating angiogenesis, stem cell mobilization, and anti-inflammatory pathways. HBOT has been shown in clinical studies to lengthen telomeres and reduce senescent cell populations, making it one of the few interventions with demonstrated biological age reversal.Learn about HBOT at Evolve Longevity
- Healthspan#
- Healthspan refers to the number of years a person lives in good health, free from chronic disease, disability, and significant functional decline. It is distinguished from lifespan, which measures total years alive regardless of health status. The central goal of longevity medicine is to extend healthspan so that it closely matches lifespan, compressing the period of morbidity and decline into as short a window as possible at the end of life.
- Hormesis#
- Hormesis is a biological phenomenon in which exposure to a low or moderate dose of a stressor that would be harmful at higher doses triggers beneficial adaptive responses in the organism. Examples include cold plunge therapy, heat exposure (sauna), high-intensity exercise, and intermittent fasting, all of which activate cellular defense mechanisms such as autophagy, heat shock proteins, and antioxidant enzyme upregulation. Hormesis is a foundational principle of biohacking and longevity optimization.
I
- Immune System#
- The immune system is a complex network of cells, tissues, and organs that work in concert to defend the body against pathogens, eliminate damaged cells, and maintain tissue homeostasis. It comprises the innate immune system (providing immediate, non-specific defense) and the adaptive immune system (generating targeted, memory-based responses). Age-related immune decline, known as immunosenescence, increases susceptibility to infections and cancer and is a key target of longevity interventions including thymic peptides and immune-modulating therapies.
- Inflammation#
- Inflammation is the body's protective biological response to tissue injury, infection, or cellular stress, characterized by redness, swelling, heat, and pain at the acute level. While acute inflammation is essential for healing, chronic low-grade systemic inflammation (often called "inflammaging") is a primary driver of nearly all age-related diseases including cardiovascular disease, neurodegeneration, cancer, and metabolic syndrome. Measuring and reducing chronic inflammation through biomarkers like hs-CRP, IL-6, and TNF-alpha is a cornerstone of longevity medicine.
- IV Therapy (Intravenous Therapy)#
- IV therapy is the administration of fluids, vitamins, minerals, amino acids, and therapeutic compounds directly into the bloodstream through a vein, bypassing the digestive system entirely. This route of delivery achieves 100% bioavailability and allows for therapeutic concentrations that are impossible to reach through oral supplementation. Common longevity IV protocols include NAD+ infusions, high-dose vitamin C, glutathione pushes, Myers' Cocktail, and custom amino acid blends tailored to individual needs.Explore our full IV therapy menu
L
- Longevity#
- Longevity refers to the duration of an individual's life, and in the context of longevity medicine, specifically to the pursuit of extending both maximum lifespan and healthspan through scientific intervention. Modern longevity science targets the hallmarks of aging, including genomic instability, telomere attrition, epigenetic alterations, mitochondrial dysfunction, and cellular senescence. The field integrates diagnostics, therapeutics, and lifestyle optimization into a comprehensive strategy for slowing and potentially reversing biological aging.Discover our longevity programs
- Lymphatic System#
- The lymphatic system is a network of vessels, nodes, and organs that runs parallel to the circulatory system and is responsible for immune surveillance, fluid balance, and the removal of cellular waste and toxins from tissues. Unlike the cardiovascular system, the lymphatic system has no central pump and relies on muscle movement, breathing, and external stimulation for flow. Impaired lymphatic drainage contributes to chronic inflammation, edema, and toxin accumulation, which is why lymphatic support therapies are integral to detoxification and recovery protocols.Learn about lymphatic drainage therapy
M
- Metabolic Health#
- Metabolic health refers to the optimal functioning of the body's energy production and utilization systems, characterized by stable blood sugar, healthy lipid levels, normal blood pressure, appropriate waist circumference, and absence of insulin resistance. Only an estimated 12% of American adults are considered metabolically healthy by these criteria. Poor metabolic health accelerates biological aging and increases risk for type 2 diabetes, cardiovascular disease, and neurodegenerative conditions.
- Mitochondria#
- Mitochondria are double-membraned organelles present in nearly every cell that produce the majority of cellular energy in the form of ATP through oxidative phosphorylation. Often called the powerhouses of the cell, they also regulate apoptosis, calcium signaling, and reactive oxygen species (ROS) production. Mitochondrial dysfunction is recognized as one of the nine hallmarks of aging, and therapies that support mitochondrial function, including NAD+ supplementation, CoQ10, red light therapy, and the peptide SS-31, are central to longevity protocols.Explore mitochondrial support therapies
- MOTS-c#
- MOTS-c is a mitochondrial-derived peptide encoded within the mitochondrial genome that functions as a powerful regulator of metabolic homeostasis and exercise mimicry. It activates AMPK (AMP-activated protein kinase), enhances glucose uptake, improves insulin sensitivity, and promotes fat oxidation, essentially mimicking the metabolic benefits of exercise at the cellular level. MOTS-c levels decline with age, and exogenous supplementation is being studied as a therapeutic approach for metabolic disease, obesity, and age-related functional decline.Learn about MOTS-c peptide therapy
- Myers' Cocktail#
- The Myers' Cocktail is a well-established intravenous nutrient infusion originally developed by Dr. John Myers, consisting of a balanced blend of magnesium, calcium, B vitamins (including B12 and B6), and vitamin C. It is one of the most widely administered IV formulas in integrative medicine, used to address fatigue, migraines, fibromyalgia, acute infections, and general wellness optimization. The cocktail delivers therapeutic nutrient levels directly to cells, bypassing the limitations of oral absorption.Book a Myers' Cocktail IV session
N
- NAD+ (Nicotinamide Adenine Dinucleotide)#
- NAD+ is a critical coenzyme found in every living cell that is essential for energy metabolism, DNA repair, sirtuin activation, and hundreds of other enzymatic reactions. NAD+ levels decline by approximately 50% between the ages of 40 and 60, contributing to mitochondrial dysfunction, impaired DNA repair, and accelerated aging. IV NAD+ infusions are used in longevity medicine to rapidly restore cellular NAD+ levels, supporting cognitive function, energy production, and the activity of longevity-associated sirtuins.Learn about our NAD+ IV therapy
- Neuroplasticity#
- Neuroplasticity is the brain's ability to reorganize its structure and function by forming new neural connections throughout life in response to learning, experience, injury, or therapeutic intervention. This capacity underlies cognitive recovery after brain injury, skill acquisition, and memory formation. Longevity interventions that enhance neuroplasticity include nootropic peptides like Dihexa and Semax, HBOT, photobiomodulation, and lifestyle factors such as exercise, sleep optimization, and cognitive challenge.Explore brain-health peptides
- Nootropics#
- Nootropics are substances, both natural and synthetic, that enhance cognitive function including memory, focus, creativity, motivation, and executive function. They work through various mechanisms such as increasing cerebral blood flow, modulating neurotransmitter levels, reducing neuroinflammation, and supporting mitochondrial function in neurons. Peptide-based nootropics such as Selank, Semax, and Dihexa represent a newer generation of cognitive enhancers with targeted mechanisms and favorable safety profiles compared to traditional stimulants.Explore nootropic peptides
O
- Oxidative Stress#
- Oxidative stress is a state of imbalance between the production of reactive oxygen species (free radicals) and the body's ability to neutralize them with antioxidant defenses. Chronic oxidative stress damages DNA, proteins, and cell membranes, accelerating the aging process and contributing to diseases including cancer, cardiovascular disease, and neurodegeneration. Key antioxidant interventions in longevity medicine include IV glutathione, high-dose vitamin C, NAD+ replenishment, and molecular hydrogen therapy.
- Ozone Therapy#
- Ozone therapy is a medical treatment that introduces ozone (O3), a highly reactive form of oxygen, into the body to stimulate oxygen metabolism, modulate the immune system, and enhance the body's antioxidant defense systems. It can be administered through various routes including intravenous (major autohemotherapy), rectal insufflation, and EBOO. Ozone therapy activates Nrf2 pathways, upregulates endogenous antioxidant enzymes, and has demonstrated antimicrobial, anti-inflammatory, and circulation-enhancing effects in clinical research.Learn about EBOO ozone therapy
P
- PEMF (Pulsed Electromagnetic Field Therapy)#
- PEMF therapy uses devices that emit pulsed electromagnetic fields at specific frequencies and intensities to penetrate the body and stimulate cellular repair processes. It enhances circulation, reduces inflammation, accelerates bone healing, and supports cellular energy production by optimizing the charge differential across cell membranes. FDA-cleared for bone healing and pain management, PEMF is increasingly used in longevity and sports recovery settings for its systemic regenerative effects.Explore PEMF therapy at Evolve Longevity
- Peptides#
- Peptides are short chains of amino acids (typically 2-50 residues) that act as highly specific signaling molecules in the body, binding to receptors on cell surfaces to trigger precise biological responses. Unlike broad-spectrum pharmaceuticals, therapeutic peptides mimic the body's own regulatory molecules, offering targeted effects with generally favorable side-effect profiles. In longevity medicine, peptide therapy encompasses tissue repair (BPC-157, TB-500), growth hormone release (CJC-1295, Ipamorelin), cognitive enhancement (Dihexa, Semax), and anti-aging (Epithalon, GHK-Cu).Explore our complete peptide therapy menu
- Photobiomodulation (PBM)#
- Photobiomodulation is the therapeutic use of specific wavelengths of red (630-670nm) and near-infrared (810-850nm) light to stimulate cellular function, primarily by enhancing mitochondrial cytochrome c oxidase activity and ATP production. It reduces inflammation, accelerates wound healing, promotes collagen synthesis, and has demonstrated neuroprotective effects in clinical studies. Also known as low-level laser therapy (LLLT), PBM is a non-invasive modality used for pain management, skin rejuvenation, and neurological recovery.Learn about red light therapy
- Placental Matrix#
- Placental matrix refers to processed tissue derived from donated human placental membranes that is rich in growth factors, cytokines, extracellular matrix proteins, collagen, and hyaluronic acid. In regenerative medicine, placental matrix allografts are used as biological scaffolds that support tissue repair, modulate inflammation, and promote healing in joints, soft tissues, and surgical sites. These products harness the natural regenerative properties of placental tissue, which evolved to support rapid fetal growth and development.Explore regenerative medicine treatments
R
- Rapamycin#
- Rapamycin (sirolimus) is an mTOR (mechanistic target of rapamycin) inhibitor originally developed as an immunosuppressant that has emerged as one of the most promising pharmacological agents in longevity research. Low-dose, intermittent rapamycin has extended lifespan in every organism tested, from yeast to mammals, and works by inhibiting mTOR complex 1 to promote autophagy, reduce cellular senescence, and enhance immune function. It is increasingly prescribed off-label by longevity physicians as part of comprehensive anti-aging protocols.
- Red Light Therapy#
- Red light therapy is a non-invasive treatment that delivers concentrated wavelengths of red (630-670nm) and near-infrared (810-850nm) light to the skin and deeper tissues to stimulate cellular energy production and biological repair processes. It works by activating cytochrome c oxidase in the mitochondrial electron transport chain, increasing ATP synthesis, reducing oxidative stress, and triggering beneficial gene expression changes. Clinical applications include pain reduction, skin rejuvenation, wound healing, joint health, and neurological support.Book red light therapy at Evolve Longevity
- Regenerative Medicine#
- Regenerative medicine is a branch of translational research and clinical practice focused on repairing, replacing, or regenerating human cells, tissues, and organs to restore normal function. It encompasses stem cell therapy, exosome therapy, platelet-rich plasma (PRP), growth factor applications, and tissue engineering. Unlike conventional medicine that manages symptoms, regenerative medicine aims to address the underlying cause of tissue damage and activate the body's intrinsic healing mechanisms.Explore regenerative medicine at Evolve Longevity
S
- Senescent Cells#
- Senescent cells, often called zombie cells, are cells that have permanently exited the cell cycle and can no longer divide but refuse to undergo apoptosis. They accumulate in tissues with age and secrete a toxic cocktail of inflammatory cytokines, proteases, and growth factors (the SASP) that damage surrounding healthy cells and tissues. The targeted elimination of senescent cells through senolytic drugs or therapies is one of the most promising frontiers in aging research, with studies showing rejuvenation of multiple organ systems following senescent cell clearance.
- Senolytics#
- Senolytics are a class of drugs and natural compounds that selectively induce apoptosis (programmed cell death) in senescent cells while sparing healthy cells. Leading senolytic agents include the drug combination dasatinib plus quercetin, fisetin, and navitoclax. Animal studies have demonstrated that senolytic treatment improves cardiovascular function, enhances physical performance, reduces frailty, and extends both healthspan and lifespan, with several human clinical trials now underway.
- Shockwave Therapy (ESWT)#
- Extracorporeal shockwave therapy (ESWT) uses focused or radial acoustic pressure waves to stimulate tissue repair, neovascularization, and collagen remodeling in targeted areas of the body. It mechanically disrupts calcifications, stimulates growth factor release, and activates mesenchymal stem cells within treated tissues. Shockwave therapy is used in regenerative medicine for tendinopathies, musculoskeletal pain, erectile dysfunction, and wound healing, with the advantage of being non-invasive and requiring no downtime.Learn about shockwave therapy
- Stem Cells#
- Stem cells are undifferentiated cells with the unique ability to self-renew and differentiate into specialized cell types including muscle, bone, cartilage, nerve, and organ tissue. In regenerative medicine, mesenchymal stem cells (MSCs) are most commonly used therapeutically for their ability to modulate the immune system, reduce inflammation, and stimulate tissue repair through paracrine signaling. Stem cell therapy represents a paradigm shift from symptom management to biological regeneration and is applied to orthopedic injuries, autoimmune conditions, neurological disorders, and systemic aging.Learn about stem cell therapy at Evolve Longevity
T
- TB-500 (Thymosin Beta-4)#
- TB-500 is a synthetic version of Thymosin Beta-4, a naturally occurring 43-amino-acid peptide found in nearly all human and animal cells that plays a central role in tissue repair, cell migration, and angiogenesis. It promotes healing by upregulating actin, a cell-building protein, which enables cells to migrate to sites of injury and form new blood vessels. TB-500 is widely used in regenerative and sports medicine for its ability to accelerate recovery from muscle tears, tendon injuries, and surgical procedures.Learn about TB-500 peptide therapy
- Telomerase#
- Telomerase is a ribonucleoprotein enzyme that adds repetitive nucleotide sequences (TTAGGG in humans) to the ends of chromosomes, counteracting the progressive shortening of telomeres that occurs with each cell division. While most adult somatic cells express little to no telomerase, certain cells including stem cells, immune cells, and cancer cells maintain high telomerase activity. Activating telomerase through peptides like Epithalon, lifestyle interventions, and certain compounds is a key strategy in longevity medicine for preserving cellular replicative capacity.Explore Epithalon for telomerase activation
- Telomeres#
- Telomeres are repetitive DNA sequences (TTAGGG) and associated proteins that cap the ends of chromosomes, protecting genetic material from degradation, fusion, and loss during cell division. Telomeres shorten with each replication cycle, and critically short telomeres trigger cellular senescence or apoptosis, functioning as a biological clock for cellular aging. Telomere length measured from blood samples serves as a biomarker of biological age, and interventions including HBOT, lifestyle modification, and telomerase-activating peptides aim to preserve or restore telomere integrity.Learn about HBOT for telomere lengthening
V
- Visceral Fat#
- Visceral fat is metabolically active adipose tissue located deep within the abdominal cavity, surrounding vital organs including the liver, pancreas, and intestines. Unlike subcutaneous fat stored under the skin, visceral fat acts as an endocrine organ, secreting inflammatory cytokines, hormones, and free fatty acids that drive insulin resistance, cardiovascular disease, and systemic inflammation. Visceral fat levels are accurately measured via DEXA scan and are a stronger predictor of metabolic disease risk than total body weight or BMI.Measure your visceral fat with a DEXA scan
- VO2 Max#
- VO2 max (maximal oxygen uptake) is the maximum rate at which an individual can consume oxygen during intense exercise, expressed in milliliters of oxygen per kilogram of body weight per minute (mL/kg/min). It is widely regarded as the single best predictor of cardiovascular fitness and all-cause mortality, with research by Dr. Peter Attia and others showing that high VO2 max confers the greatest reduction in mortality risk of any measurable fitness parameter. Clinical VO2 max testing with metabolic analysis provides actionable data for optimizing training protocols and tracking cardiovascular health over time.Book a VO2 max test at Evolve Longevity
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